Speaking at the annual AusBiotech conference in Sydney, Dr Woodrow, told leaders of the biotechnology industry that there was a clear alignment between the capabilities at CSIRO and the needs of the biotech industry and that together they could deliver a great impact for Australia.
“The partnership with AWI is employing new molecular tools developed by CSIRO scientists working to aid the discovery of new insecticides for sheep pests."
“Biotech companies rely critically on innovation to succeed, yet much of that innovation requires capital-intensive infrastructure and multi-disciplinary scientific capabilities. Most individual companies do not have these but CSIRO does and this is precisely where CSIRO can help,” Dr Woodrow said.
The technique used to discover the 3D shape of each receptor protein is called structural biology. X-rays are passed through crystals of the pure protein and from the data obtained a 3D structure of the molecule is determined.
A well known human health success story employing this technique is the development of the anti-flu drug Relenza.
There is an historical link between the development of Relenza and the current discovery program for new insecticides. The idea for looking at the ecdysone receptor protein and then designing molecules to mimic the hormone binding to it came from CSIRO's pioneering research on influenza proteins.
Commonwealth Scientific and Industrial Research Organisation
marketing@alchempro.com
